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Clinical Trials

Pentucket Medical is committed  in improving and offering  advanced treatments. We do this by being involved in several clinical trials. These trials have brought about successful outcomes such as:

  • 3 trials for atrial fibrillation where the drugs were approved by the FDA
  • 2 trials for heart failure where the drug was approved by the FDA
  • 1 trial that helped change the guidelines for post heart attack patients.

We are currently enrolling participants who have: 

  • Had Heart failure
  • Diabetes
  • Had a prior heart attack
  • High cholesterol

If you are interested in participating in one of our clinical trials click the links below Active Studies.


To find out whether you are eligible to participate in one of these studies, please contact the Clinical Research Office at (978) 469-5494.

Active Studies

Clinical trials are entirely voluntary and patients may withdraw at any time, for any reason. We are currently participating in the following studies:


A Randomized, Double-blind, Placebo-controlled, Event-driven trial of Weekly Low-dose Methotrexate (LDM) in the Prevention of Recurrent Cardiovascular Events Among Stable Post-Myocardial Infraction Patients with Type 2 Diabetes or Metabolic Syndrome.

Trials Closed to Enrollment

Currently in follow up phase:


A double-blind, randomized, placebo-controlled, multicenter study assessing the impact of additional ldl-chloesterol reduction on major cardiovascular events when used in combination with statin therapy in patients with clinically evident cardiovascular disease


A randomized, double-blind, placebo-controlled, event driven trial of quarterly subcutaneous canakinumab in the prevention of recurrent cardiovascular events among stable post-myocardial infarction patients with elevated hsCRP


Dapagliflozin Effect on Cardiovascular Events: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Effect of Dapagliflozin 10mg Once Daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Ischemic Stroke in Patients with Type 2 Diabetes

COVID-19 testing is available by referral only.

Please contact your health care provider for an appointment. 

Safe Care Commitment

To everyone who needs us now, come get the care you deserve. Our Safe Care Commitment is in effect across our system to provide the safest possible environment for our patients, visitors and staff.

We screen to protect you, your families, and our staff.

We clean our hands and spaces and make it easy for you to do the same.

We protect everyone in our environment.